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Urine Examination (Routine)

Also known as: Urine

Sample Type

Urine

Tube Type

EDTA Tube

Fasting Required

No

Lab

Serum

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Overview

A Urine Routine Examination (Urinalysis) is a commonly performed diagnostic test that analyzes the physical, chemical, and microscopic characteristics of urine. It is used to detect:

  • Urinary tract infections (UTIs)

  • Kidney disorders

  • Liver problems

  • Metabolic conditions (e.g., diabetes)

  • Dehydration or electrolyte imbalance

The test is typically divided into three components:

  1. Physical Examination – Color, clarity, and specific gravity.

  2. Chemical Examination – pH, proteins, glucose, ketones, bilirubin, blood, nitrites, etc.

  3. Microscopic Examination – Cells, crystals, casts, bacteria, and other substances.

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Test Result Interpretation

Physical Characteristics:

Parameter

Normal Range/Appearance

Abnormal Findings & Interpretation

Color

Pale yellow to amber

Dark: dehydration; Red/pink: hematuria; Cloudy: infection

Clarity (Appearance)

Clear

Cloudy/turbid: UTI, crystals, cells

Specific Gravity

1.003 – 1.030

Low: overhydration, renal failure; High: dehydration, glycosuria

Chemical Characteristics:

Parameter

Normal Value

Abnormal Findings & Interpretation

pH

4.5 – 8.0

Acidic: diabetes, starvation; Alkaline: UTI, vegetarian diet

Protein

Negative

Positive: kidney disease (proteinuria), nephrotic syndrome

Glucose

Negative

Positive: uncontrolled diabetes mellitus

Ketones

Negative

Positive: starvation, diabetic ketoacidosis

Bilirubin

Negative

Positive: liver disease, biliary obstruction

Urobilinogen

0.1 – 1.0 mg/dL

High: hemolysis, liver disease; Low: biliary obstruction

Blood

Negative

Positive: infection, trauma, kidney stones, menstruation contamination

Nitrites

Negative

Positive: bacterial infection (usually gram-negative bacteria)

Leukocyte Esterase

Negative

Positive: presence of white blood cells (suggestive of UTI)

Microscopic Examination:

Component

Normal Finding

Abnormal Interpretation

RBCs (Red Blood Cells)

0–2 / HPF

Hematuria: UTI, stones, trauma, glomerulonephritis

WBCs (White Blood Cells)

0–5 / HPF

Pyuria: UTI, inflammation

Epithelial Cells

Few

Increased: contamination or renal tubular damage

Casts

None or occasional hyaline

RBC casts: glomerulonephritis; WBC casts: pyelonephritis; Granular casts: tubular damage

Crystals

None to few (depending on diet)

Excess: stone formation, metabolic disorder

Bacteria/Yeast

None

Present: infection (UTI or candidiasis)

Mucus Threads

Occasional

Increased: nonspecific; may occur in UTI or irritation

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Risk Assessment

  • Urine samples should be fresh (ideally within 1 hour of collection) to avoid false positives/negatives.

  • A clean-catch midstream sample is preferred to reduce contamination.

  • Follow-up may include urine culture, renal function tests, or imaging depending on findings.

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